In a more and more frequent scenario of global epidemics and natural catastrophes, we face the need of efficient laboratory structures where diagnostic procedures, quality control analysis, environmental analysis, treatment procedures and other operations in which biological risk is a reality, can be prepared and manipulated in proper containment conditions.
Along with demanding situations such as pandemics, comes the hard reality of prolonged processes for design development, deployment and implementation of suitable laboratory structures. This is particularly worrying in remote areas of the planet where time runs very slowly and problems tend to accumulate too quickly.
Conventional laboratory facilities require procedures that sometimes take years to be developed and implemented. Increasing demand for short-time operational and deployment alternatives to such facilities, is triggering the development of a new laboratory concept. Quick implementation of laboratory facilities, such as biological containment laboratories, is indispensable to support a faster response to populations in critical situations and avoid more severe consequences.
Maritime containers present a fitting structure for implementation of BSL 2 and BSL3 laboratories and, at the same time, suitable for exportation of ready-to-operate facilities to any part of the globe while fully respecting World Health Organization (WHO) recommendations.
Type Project presents itself as a company capable of developing solutions, designing and installing cleanroom facilities and HVAC systems, adaptable to every space. The company provides modern, high-tech and functional laboratory equipment prepared to confer results in record time with complete confidence and carefully selected to fit the installation.
LAB2GO is a turnkey product capable of solving the aforementioned problems by offering a portable, fast deployment and ready to operate alternative to conventional BSL 2 and BSL 3 laboratories.
LAB2GO is a ready-to-use solution comprising all features, each of them elaborated and improved individually to fulfill the requirements and promote a more dynamic and agile workflow, including:
o Adjustable layout and design;
o Adapted to be connected to other LAB2GO units;
o Detailed, custom-made and unique architecture, including our own TypeAir ventilation modules;
o Advanced HVAC system specific for Level 2 and 3 containment;
o Modern and efficient laboratory equipment;
o A computer for monitoring of the inside environment, equipment, and data saving;
o Type Project furniture: ergonomic features and designed with hygienic and resistant material to suit your laboratory needs;
o Adequate training of operators/technicians;
o Operators’ training and support through audio-visual content accessible at any time;
o Energy efficiency according to ISO 14644-16;
o Smart materials for energy needs and wastewater treatment;
o Overseas preventive maintenance.
The LAB2GO project was developed in compliance with current standards and recommendations for specific biosafety facilities, considering the WHO’s classification and the construction and validation requirements for cleanrooms, such as:
o EU GMP Annex I, Manufacture of Sterile Medicinal Products;
o Annex 2A – PIC/S GMP;
o WHO (2020), Laboratory Biosafety Manual – 4th Edition;
o Regulation (EC) No 1394/2007;
o EN 12128 (2000) – Biotechnology – Laboratories for research, development and analysis – Containment levels of microbiology laboratories, areas of risk, localities and physical safety requirements;
o ISO 14644-1/4, Cleanrooms and Associated Controlled Environments;
o USP <1116>, Microbiological Control of Aseptic Processing Environments and its implications;
o Filter efficiency according to standards (CEN, British Standard BS2646, ISO, ANSI, ASHRAE);
o PIC/S PE 010-4, Guide to Good Practices for the Preparation of Medicinal Products in Healthcare Establishments;
o Materials: compliance with international standards (ASTM, ASME, CEN, ISO) as well as current legislation. Certificates must comply with EN 10204 (Certificate 3.1B) and / or ASTM E1831.
Maritime containers are widely used to house technology equipment and as healthcare temporary workstations. These containers offer high durability, are waterproof, capable to handle extreme outdoor conditions and are a cost-effective solution. They are easily movable and can be shipped by air, sea or land.
Exterior (LxWxH): 12,20 x 2,44 x 2,90 m (40,02 x 8,00 x 9,51 ft)
Interior (LxWxH): 12,03 x 2,35 x 2,70 m (39,46 x 7,70 x 8,85 ft)
Designed to fully comply with the WHO’s biosafety requirements for BSL 2 and BSL 3, LAB2GO includes independent airlocks to access and exit the biocontainment laboratory, as well as air pressure differentials between rooms. These features allow the achievement of a greater and most suitable containment level.
The biocontainment laboratory, where all the biological risk procedures take place, is located at the centre of the facility, giving access to a technical room where the entire support equipment and HVAC device will be installed.
Customization and design of LAB2GO results of a structured risk assessment and risk control measures developed by our team of specialists. This assessment requires knowledge regarding the type of work to be carried out inside the unit, the correct environment in which the procedures should be conducted and the biological agents to be manipulated within the unit.
Surfaces and finishes of the LAB2GO unit such as ceiling panels, wall panels, floor, windows, and light fixtures were selected to provide smooth, dust-free areas to avoid the release of particles in the room and to facilitate cleaning and disinfection procedures. Also, our structures are scratch- and damage-resistant and due to the modular cleanroom wall panels design, it is easy to modify the unit layout at any time or replace a single panel if needed.
Personnel Flow Areas
LAB2GO facilities are designed to reinforce all safety measures so that the operator and the environment are effectively protected. Higher protection can be achieved by two main design layout features: Firstly, by the implementation of two entry/exit airlocks (represented as reception room airlock and entry/exit airlock) in order to enter the biocontainment laboratory (cabinet room and secondly, by physical separation between sample and personnel flow areas. LAB2GO layout also considers a shower room between changing areas.
Entrance of samples from the exterior of the container to the lab’s interior is performed through a ventilated passbox, while personnel must enter through the two airlocks mentioned above.
Sample Flow Areas
LAB2GO solution contemplates an Isolator which ensures complete protection of the product, operator and environment, and allows considerable energy savings. This advanced technology is negatively pressurized offering not only a physical barrier between the operator and the product, but also providing a safer and controlled environment . Additionally, it increases energy saving due to the possibility of working in a class D biocontainment laboratory instead of B. The Isolator and the pass box have a higher negative pressure compared to the room atmosphere and the sterile chamber (PCR chamber), where the master mix is prepared, is decontaminated with UV light and has a positive pressure, allowing not only a complete separation between the operator and the sample, but also the possibility to perform the entire procedure in the same room.
Waste Disposal – Autoclave
Barrier-type decontamination systems, like double-ended autoclaves, are essential for a higher safety level as it further reduces the proliferation of potentially dangerous microorganisms. Wearable items are placed inside the double-door containment autoclave and after being decontaminated they can be collected from a separated room.
“A double-door, pass-through autoclave must be available in the laboratory area for decontamination of laboratory materials, equipment and solid waste”
– WHO, “Laboratory Biosafety Manual, fourth edition”
Biosafety Cabinet – Centralized HVAC System
The LAB2GO Unit is designed to have 100% air exhaust and air filter system including HEPA filters, and air pressure differential, to promote containment and prevent contamination according to the WHO’s recommendation for BSL 2 and BSL 3 biosecurity level.
Air insufflation is designed to be carried out along the entire false ceiling, while the air extraction is designed to be carried out by the brand new TypeAir modules.
For better comprehension of the 2D floorplans we have created the 3D visualization model to extend the customer’s experience in this concept.
Product, Operator and Environment Protection
Our technical solution offers our clients the possibility to acquire a portable hydrogen peroxide (H2O2) biodecontamination bag system aiming at the protection of the product, operator and environment which includes the implementation of insulator technology with its H2O2 decontamination system extended to the overall installation.
Inspired by the need of furniture surfaces’ cleaning in critical areas and critical applications, Type Project designs its furniture with innovative and specially adapted materials to each application, equipment and operators. This modern and customized furniture is found in your LAB2GO offering security and innovation to our customers.
The furniture chosen to be a part of this project was carefully designed to obtain the stability and sanitized environment needed for the BSL 2 and BSL 3 requirements.
The reinforced worktop’s legs are built to endure shock taken during transportation of the portable lab being fixed to the floor. The material used on the workspace is made of high-density fibers with an electric beam cure coated by a decorative surface which makes this material highly chemical resistant, antibacterial and fireproof.
We recognize safety and comfort as the most important features to be successful in such erratic times and therefore we have improved our product by providing a centralized management system (CTM) that allows you to control, monitor and operate all elements installed inside the containment unit.
We offer the possibility to have the HVAC system components remotely controlled and programmed, enabling Type Project to ensure its smooth operation anywhere.
Recommendation and installation instructions as well as operator’s training are programmed to be achieved through an advanced audio-visual system with real time follow- up of our multidisciplinary experts
The proposed standard LAB2GO unit includes:
o Container 40’ high cube;
o Cleanroom surfaces and finishes;
o Customized Isolator or Class III Biological Safety Cabinet (BSC);
o Ventilated passbox;
o Cleanroom lightning;
o Portable decontamination system;
o HVAC system;
o Type Project furniture;
o Operators training and support, through audio-visual content accessible at any time;
o Electrical supplies with power stabilizer.
On demand we also provide:
o Overseas preventive maintenance and centralized management system (CTM);
o Centralized hydrogen peroxide decontamination system;
o Decontamination shower chamber;
o Inflated gaskets for main doors;
o Compressed air equipment.